Ontonix Develops Risk Stratification Tool for Multimorbidity AF Patients

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Como, 20-th July, 2023. Ontonix, a technology company delivering Quantitative Complexity Management (QCM) hardware and software (HW & SW) for early warnings and anomaly detection, has developed Risk Stratification Tool for Multimorbidity Atrial Fibrillation Patients.

In the framework of the European Horizon Project AFFIRMO, grant 899871, Ontonix has developed a Risk Stratification tool which provides a probability score of patient hospitalization within a 1-year period. The specific aim of the AFFIRMO project is to implement and test the effectiveness of an integrated patient-centered holistic care pathway for the management of older patients with AF and multimorbidity, which will facilitate cooperation among different health disciplines and promote a shared decision-making processchronic conditions.

The work has been performed within a work package led by the Karolinska Institute in Stockholm, where the tool is being tested. Tests with batches of 2450 and 3100 patients, show a hit ratio of 92% and the Area Under the ROC Curve (AUC) of 0.86.

“The tool may be adapted to process other types of data, such as that collected from pacemakers/ICDs implanted in patients with cardiac disorders, providing an improved and patient-specific post-implant care and monitoring”, said Dr. J. Marczyk, the CEO of Ontonix. “Participation in the AFFIRMO consortium has enabled us to develop this new tool which will now be made available to our clients for evaluation and testing”, he concluded.

The goal of the AFFIRMO project (Atrial Fibrilation integrated approach in Frail, multimoRbid and polyMedicated Older people) is to implement the effectiveness of an integrated patient-centered holistic care pathway for the management of older patients with Atrial Fibrillation and multimorbidity, which will facilitate cooperation among different health disciplines and promote a shared decision-making process. The final result will be to provide comprehensive management of AF, which being tailored in the context of coexisting disease and patient preferences can potentially lead to a reduction in physical and mental impairment allowing the older patient to cope better with multimorbidity. The project (899871) has a duration of five years. For more information visit AFFIRMO.

Ontonix develops early-warning systems for medical applications based on its Artificial Intuition technology. For more information visit site.

For information on Ontonix, visit www.ontonix.com/

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Dr. Jacek Marczyk

Visionary, ex rocket scientist, businessman and writer with over 35 years of experience in QUANTITATIVE large-scale Uncertainty and Complexity Management in diverse fields (manufacturing, finance, economics).

Author of ten books on simulation, uncertainty and complexity management, rating.

Developed in mid 90s the theory of eigenvalue orbits, a generalization of the concept of eigenvalue.

In 2000-2005 has developed the first Quantitative Complexity Theory (QCT), including a comprehensive measure of complexity.

Founded Ontonix Complexity Management in 2005 in the USA and launched in 2006 the first commercial system for MEASURING and managing complexity: OntoSpace.

www.ontonix.com

In 2009 developed real-time technology to measure the complexity and stability of patients during operation or permanence in Intensive Care Units.

http://www.ontomed.net

Developed a new theory of risk and rating published in 2009 in a book entitled "A New Theory of Risk and Rating".

Over last decade develops quantitative complexity management (QCM) technology and solutions for applications in economics, finance, Risk Rating and Management as well as in Asset Management and medicine. In the past five years works towards the democratization of ratings.